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Calcitonin is produced in para-follicular C cells of the thyroid gland and is implicated in the regulation of circulating levels of calcium (Foster et al., 1964). Calcitonin is a peptide of 32 residues and circulates under different isoforms depending on the processing state of the hormone. This molecular heterogeneity might affect its measurement. Calcitonin levels may be increased in C cell diseases or in other diseases such as chronic renal failure, neuroendocrine tumors or autoimmune thyroid disease (Costante et al., 2009).

Bioclinica Lab employs a sandwich chemiluminescent immunoassay (CLIA) designed to measure calcitonin in human serum.


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