Please Wait...

Neurogranin

Biomarker Therapeutic Areas: 
Biomarker Matrices: 

Neurogranin is a post-synaptic protein regulating synaptic plasticity, learning and memory consolidation. Neurogranin is thought to be involved in activity-dependent synaptic plasticity and long-term potentiation through the modulation of calcium-mediated signaling pathways. Because of its abundant and preferential neuronal expression, Neurogranin has been identified as a potential marker of neurodegeneration in large-scale gene arrays,  along with other candidate markers such as VILIP-1 (Laterza et al., 2006). Several studies have shown that CSF Neurogranin levels are increased in AD, even at the early clinical stages, and could predict cognitive deterioration (Janelidze et al., 2015; Portelius et al., 2015; Sun et al., 2016; Thorsell et al., 2010).

Bioclinica Lab employs a manual sandwich immunoassay designed for the measurement of Neurogranin in human cerebrospinal fluid.

ADDITIONAL RESOURCES

Biomarker Menu

Download MENU

Molecular Marker Laboratory Services

Download Brochure

Alzheimer's Disease Biomarker Lab Expertise

Download Info Sheet

Leader in Clinical Trial
Management Solutions

Successful clinical trials require the ability to see key details and uncover hidden insights. Bioclinica utilizes science and technology to bring clarity to clinical trials, helping companies to develop new life-improving therapies more efficiently and safely.

Still time to catch up on summer reading on recent developments in #Alzheimer's Disease Fluid Biomarkers here int t… https://t.co/kyQmz7FxlN
bioclinica (Yesterday)
Our clients have substantial success w #eSource, some spanning well over a decade. Still other organizations remain… https://t.co/UwVs6ajPp4
bioclinica (2 days ago)
Our clients have substantial success w #eSource, some spanning well over a decade. Still some in the industry remai… https://t.co/ASuUvN6xb9
bioclinica (4 days ago)
RT @RfwrightLSL: When Do You Think #BYOD (Bring Your Own Device) Will Become Widely Used To Capture PRO Data In #Clinical #Research? https:…
bioclinica (1 week ago)
ICYMI: Our V.P./Head of Neuroscience & Cardiovascular Svcs., Dr. Joyce Suhy, talks about challenges in determining… https://t.co/Lns6B3VPPN
bioclinica (1 week ago)
RT @FCR_News_Today: FDA Issues New Guides on Use of Electronic Health Information in #ClinicalTrials. #ClinicalResearch https://t.co/j8LHV2…
bioclinica (2 weeks ago)

Latest Blogs:

Latin America: Benefit from the Right Partner
Removing Risk from Clinical Trial Management System (CTMS) Implementations
Collaboration Between Clinical Operations and the Logistics and Supply Chain Teams is Key to Trial Success
The Value of Protocol Review
CTMS and RBM: Hot Topics at OCT Nordics in Copenhagen