Please Wait...

PSA // Prostate Specific Antigen

Biomarker Therapeutic Areas: 
Biomarker Matrices: 

Prostate Specific Antigen (PSA) is a member of the Kallikrein related peptidase and is also known as Kallikrein-Related peptidase 3 (KLK3). Its major physiological function is the liquefaction of seminal fluid through its proteolysis activity against gel proteins. PSA is normally found in seminal fluid and only a small proportion is found in blood. The release of PSA in blood circulation is believed to be the result of architecture modification and alterations in the basement membrane when prostate tumors develop (Lilja et al., 2008). In serum, PSA can be bound to α1-antichymotrypsin or α2-macroglobulin or can circulate as free PSA (mixture of mature and pro-, nicked and intact forms of free PSA). In addition to its diagnostic value, PSA levels in serum are measured to monitor treatment response and efficacy (Fleming et al., 2006).

Bioclinica Lab employs an automated sandwich chemiluminescent immunoassay for total PSA measurement in serum.


Biomarker Menu

Download MENU

Molecular Marker Laboratory Services

Download Brochure

Alzheimer's Disease Biomarker Lab Expertise

Download Info Sheet

Leader in Clinical Trial
Management Solutions

Successful clinical trials require the ability to see key details and uncover hidden insights. Bioclinica utilizes science and technology to bring clarity to clinical trials, helping companies to develop new life-improving therapies more efficiently and safely.

We're hiring recent tech grads in #RTP for #pharma sector! Our innov. clinical financial solution gives our client…
bioclinica (3 hours ago)
Great to be @DrugInfoAssn DIA China! Ask us @bioclinica how sponsors & CROs can optimize electronic data capture…
bioclinica (9 hours ago)
RT @bioclinica: Kinks in the clinical supply chain? Check out how one of our clients is using clinical supply optimization technology for m…
bioclinica (9 hours ago)
RT @bioclinica: Welcoming everyone to KOP for #OCTEast Coast!!
bioclinica (9 hours ago)
Welcoming everyone to KOP for #OCTEast Coast!!
bioclinica (Yesterday)
Case processing is an important aspect of post-marketing drug safety surveillance. Here's a case study showing how…
bioclinica (2 days ago)

Latest Blogs:

Latin America: Benefit from the Right Partner
Removing Risk from Clinical Trial Management System (CTMS) Implementations
Collaboration Between Clinical Operations and the Logistics and Supply Chain Teams is Key to Trial Success
The Value of Protocol Review
CTMS and RBM: Hot Topics at OCT Nordics in Copenhagen