Please Wait...

PYD // Pyridinium Crosslinks

Biomarker Therapeutic Areas: 
Biomarker Matrices: 

Pyridinium Crosslinks (PYD) or Pyridinoline is a non-reducible crosslinks of collagen formed during collagen maturation. High levels of PYD are found in cartilage, in comparison with bone levels. PYD crosslinks measured in urine reflect bone resorption (Seibel et al., 1992). In bone, the crosslinks of mature collagen are: PYD and deoxypyridinoline, they are released in circulation and urine during bone resorption (Delmas, 1993). Pyridinoline crosslinks were initially measured with HPLC, but an immunoassay have been developed to allow measurement of PYD without need of HPLC techniques (Seyedin et al., 1993).

Bioclinica Lab employs a manual competitive enzyme-linked immunoassay designed for the measurement of PYD in urine.


Biomarker Menu

Download MENU

Molecular Marker Laboratory Services

Download Brochure

Alzheimer's Disease Biomarker Lab Expertise

Download Info Sheet

Leader in Clinical Trial
Management Solutions

Successful clinical trials require the ability to see key details and uncover hidden insights. Bioclinica utilizes science and technology to bring clarity to clinical trials, helping companies to develop new life-improving therapies more efficiently and safely.

RT @bioclinica: @CardiacSafety Consortium needs your feedback! Help make the upcoming think tank "Evaluation of #MobileTechnologies in #CV…
bioclinica (5 minutes ago)
@CardiacSafety Consortium needs your feedback! Help make the upcoming think tank "Evaluation of…
bioclinica (10 minutes ago)
RT @CDISC: Special thanks to CDISC Member @bioclinica for hosting CDISC Public Training in Audubon, PA 2-6 Apr 2018. Register today. https:…
bioclinica (26 minutes ago)
Bioclinica Delivers Individual Case Safety Report (ICSR) Processing w Quality & Consistency While Crossing One Mil…
bioclinica (Yesterday)
Who made the BioSpace list of 11 most innovative life sciences companies in the world? Ck it out here via @biospace…
bioclinica (Yesterday)
BREAKING: With a passion for Drug Safety, we’re delighted to share @bioclinica #pharmacovigilance crossed 1M ICSR c…
bioclinica (2 days ago)

Latest Blogs:

Latin America: Benefit from the Right Partner
Removing Risk from Clinical Trial Management System (CTMS) Implementations
Collaboration Between Clinical Operations and the Logistics and Supply Chain Teams is Key to Trial Success
The Value of Protocol Review
CTMS and RBM: Hot Topics at OCT Nordics in Copenhagen