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Interactive Response Technology (IRT)

Bioclinica's Interactive Response Technology (IRT) is the industry's only IRT system that provides advanced visibility to working study prototypes within just a few days - letting you build, implement, test and deploy new protocols in as little as two weeks, with or without customization. And this IRT integration with Bioclinica's Trial Supply Optimization software lets you identify and adjust enrollment rates and supply needs based on trial actuals, so you get to database lock faster, with significantly lower cost and effort, and with higher-quality data.

Rapid Start Up of Complex Studies


Set up, test, and deploy study protocols within weeks instead of months with Bioclinica’s IRT a parameter-driven Interactive Response Technology (IRT) solution. Because the programming is already done, little or no system development effort is required. In fact, Bioclinica’s IRT reduces the average set up time 50 to 75 percent compared to IRT systems built from the ground up for each new study.

Rapid configuration combined with robust functionality make Bioclinica’s IRT the IRT of choice for fast launch of complex clinical studies. Built-in alerts and notifications provide proactive tools that help bridge the gap between sites and supply chain management. Adaptive study design, temperature controlled supply management, and drug accountability are standard features. Additionally, a unique set of high-performance capabilities make it a best-in-class IRT for the most demanding studies.

Bioclinica’s IRT provides the ideal solution for the following:

Subject Randomization

Randomizing study subjects into treatment arms for clinical trials can be a difficult and complex undertaking. Study subject bias can be introduced during randomization. Increasingly complex study designs and treatment scenarios complicate the process. Bioclinica’s IRTsimplifies randomization and minimizes study subject allocation bias using proven statistical methods.

Additionally, Bioclinica’s IRT:

  • Re-randomizes subjects into another treatment arm for another study phase.
  • Randomizes another study subject into a treatment group to replace dropped participants without disrupting study balance.
  • Supports extension studies, rolling over qualified subjects from one study to another.

Drug Tracking, Dispensing and Reconciliation

Bioclinica’s IRT is tailored to visit-specific strata, making it easy to manage complex dosing scenarios. Because it is configurable for predictive re-supply based on actual demand, it eliminates drug supply over-stocks and stock-outs. Additional value-added features include:

  • A controlled substance inventory management tool provides tracking and monitoring to the pill level. Set customizable site inventory limit controls, shipment restrictions, and threshold alerts. Track medication status along the entire supply chain and know whether it was taken, disposed, lost, destroyed, or returned.
  • Drug pooling functionality minimizes drug waste and eliminates unnecessary labeling costs.
  • Combine IRT and Trial Supply Optimization, Bioclinica's advanced supplies simulation and forecasting tool, for a global supply management solution. Manage clinical supplies based on actual usage and forecasting consumption to significantly minimize waste and reduce costs.

User Requirement Specifications

While the IRT User Requirements Specification is short and simplified, it is fully comprehensive and designed to enable Bioclinica to define the study and match all of your parameters.

This creates a smooth process that helps eliminate errors, misunderstandings, and unwelcome surprises. Built precisely to your specifications, Bioclinica's IRT is an easy to validate IRT. Since voice and web components are integrated, there is only one system setup.

Intuitive User Experience

Bioclinica's IRT is the intuitive, easy to use IRT designed for the way users actually work. It maximizes user productivity and minimizes frustration. Clean screen layout and straightforward navigation guide users to complete tasks in logical progression. Users appreciate the ability to correct data entry errors and print reports when needed. Sites find it especially useful to access reports on their dashboard. System performance is fast and flexible and multiple languages are supported. Since it is so easy to use, training is brief — less than an hour.

Contact us to take Bioclinica's IRT for a test drive and see why Bioclinica's global customers use it for the most complicated study scenarios.


White Papers

Feasibility of shipping clinical trial drugs directly to patients' homes

Depot-to-patient dispensing is a novel approach to the distribution of study drug that can respond to the subject's clinical needs regardless of whether the visit is conducted at the clinic or via telephone.

Agile IRT: Improving Quality and Efficiency in the Study Build Process

Clinical trials are frequently required to run large numbers of patients through blinding (or masking) processes.


The Value of Protocol Review

One of our strategic customers recently invited me to review a draft protocol synopsis for a pivotal Phase III registration study. As the provider of the randomization and trial supply management (RTSM) solution  for the study, I relished the opportunity.

The clinical randomization and supply chain management systems we now dub “IRT” were initially built as fully customized IT projects, individualized and implemented separately for each study.

Join us for our upcoming webinar on September 13th during which Bioclinica experts Senior Director of RTSM Operations and Commercial Solutions, and Robin Barber, Manager of R


Bioclinica Agile RTSM

Download Overview Sheet

IRT Reporting Capabilities

Download Data Sheet

Agile IRT: Improving Quality and Efficiency in the Study Build Process

Download White Paper

Feasibility of shipping clinical trial drugs
directly to patients' homes

Download Case Study


Download Infographic

Leader in Clinical Trial
Management Solutions

Successful clinical trials require the ability to see key details and uncover hidden insights. Bioclinica utilizes science and technology to bring clarity to clinical trials, helping companies to develop new life-improving therapies more efficiently and safely.

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